Friday, March 28, 2025

Is This Gene-Editing Pioneer a Strong Buy?

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Is This Gene-Editing Pioneer a Strong Buy?

Anthony Summers, Director of Trading, The Oxford Club

Anthony Summers

Crispr Therapeutics (Nasdaq: CRSP) stands at the forefront of gene-editing technology, aiming to develop revolutionary treatments for serious diseases.

The company recently achieved a significant milestone with the approval of Casgevy, the world's first CRISPR-based therapy, which treats sickle cell disease and beta thalassemia. (CRISPR, short for "clustered regularly interspaced short palindromic repeats," is a type of genetic sequence and was the namesake of Crispr Therapeutics.)

Beyond its flagship product, Crispr Therapeutics maintains a diverse pipeline with five clinical programs and 10 preclinical programs.

The stock has experienced dramatic price swings over the past year. Since climbing from below $40 in late 2023 to a peak near $90 in early 2024, shares have dropped sharply.

Chart: Crispr Therapeutics (Nasdaq: CRSP)
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Currently trading around $40, the stock has fallen over 50% from its highs, reflecting investor uncertainty about the company's path to profitability despite its cutting-edge technology.

From a financial standpoint, Crispr Therapeutics is still in its early commercial phase. The company has spent heavily on research and development while building out its pipeline across four therapeutic areas: hemoglobinopathies, an immune cell therapy called CAR-T, in vivo approaches, and Type 1 diabetes treatments.

With a robust cash position of approximately $1.9 billion, the company has a runway to advance its clinical programs, but revenue will likely remain limited until Casgevy and other potential therapies gain wider market adoption.

So, are Crispr's strong cash hoard and promising pipeline enough to justify its current valuation? Let's find out.

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